Cold Spring Harbor Laboratory is hosting the course, Statistical Analysis of Genome Scale Data, June 5-19, 2025. Harmen Bussemaker, from Columbia University, Sean Davis, from the University of Colorado Anschutz School of Medicine, and Hans Tomas Rube, from the University of California Merced will serve as the course instructors. The class focuses on building competence in statistical methods for analyzing high-throughput data in genomics and molecular biology in both experimental and computational biologists through detailed lectures and presentations by instructors and guest speakers and hands-on computer tutorials.
Topics include:
The R environment for statistical computing and graphics
Introduction to Bioconductor
Review of basic statistical theory and hypothesis testing
Experimental design, quality control, and normalization
High-throughput sequencing technologies
Expression profiling using RNA-seq and microarrays
In vivo protein binding using ChIP-seq
High-resolution chromatin footprinting using ATAC-seq
Integrative analysis of data from parallel assays
Representations of DNA binding specificity and motif discovery algorithms
Predictive modeling of gene regulatory networks using machine learning
Applications are due by March 13th. For more information visit the course website.
